Launch from Baikonur; landing 193 km southwest of Karaganda.

The first time that more than one manned spacecraft were in orbit at the same time. Rendezvous-flight with Vostok 3 at time. Both spacecrafts came close to 5 km (visibility), although the Vostok-capsules had no maneuvering capability. They quickly drifted apart. Popovich had problems with his life support system, resulting in the cabin temperature dropping to 10 degrees Centigrade with 35% humidity conditions. But he still managed to conduct several experiments, and further improve the space ship systems, communications (spaceship-ground-control and from spaceship-to spaceship), guidance and landing. His work included taking colour motion pictures of the terminator between night and day and of the cabin interior.

Popovich had been briefed to tell ground control that he was 'observing thunderstorms' if he felt the motion sickness that had plagued Titov and would have needed to return. The problem was that he actually saw real thunderstorms over the Gulf of Mexico, a fatal misunderstanding that caused him to land one day earlier than planned.