Launch from Cape Canaveral (KSC); landing on Cape Canaveral (KSC).

Deploying of SPARTAN-201 research platform and retrieval after two days of free flying. The SPARTAN 201 free-flyer made its third flight aboard the Shuttle. The SPARTAN 201 mission was a scientific research effort aimed at the investigation of the interaction between the Sun and its outflowing wind of charged particles. SPARTAN's goal was to study the outer atmosphere of the Sun and its transition into the solar wind that constantly flows past the Earth.

Deploying of "Wake Shield Facility" (WSF-2) and retrieval after free flying. The Wake Shield Facility (WSF), a saucer shaped satellite that flew free of the Shuttle for several days. The WSF growed thin films in a near perfect vacuum created by the wake of the satellite as it moves through space.

EVA by Voss and Gernhardt on 16.09.1995 (6h 46m) to test assembly techniques for the ISS.

STS-69 saw the first flight of the International Extreme Ultraviolet Hitchhiker (IEH-1), the first of five planned flights to measure and monitor long-term variations in the magnitude of absolute extreme ultraviolet (EUV) flux coming from the Sun, and to study EUV emissions from the plasma torus system around Jupiter originating from its moon Io. Another payload was a connection to the development of the Space Station is the Electrolysis Performance Improvement Concept Study (EPICS).