Launch from the Baikonur Cosmodrome; landing 55 km northeast of Arkalyk.

Following a two day solo flight the Soyuz docked with the new space station MIR on March 15, 1986. The cosmonauts became the first resident crew of MIR.

The first work was to make the station working and to unload the two Progress 25 and 26 freighters, launched after their arrival.

On May 05, 1986, they undocked from MIR for a day long journey to the Salyut 7 space station and stayed there for 50 days as sixth resident crew. Leonid Kizim and Vladimir Soloviyov conducted two EVAs while staying on Salyut 7 on May 28, 1986 (3h 50m) and May 31, 1986 (5h 00m), repairing heat, power and environmental control systems and collecting experiment results, experimental apparatus, and samples of materials. After done work returning to MIR on June, 26, 1986. It was the first transfer from one space station to an other space station in space history.

When back on MIR Leonid Kizim and Vladimir Soloviyov installed there some systems taken from Salyut and they performed some scientific experiments. One of these experiments was GEOEX 8, in which some areas of the German Democratic Republic were explored by an airplane, a satellite and from space. This was useful for agriculture, geology and environmental protection.

Before returning back to Earth the crew put the MIR into an automatic working modus.